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Influence of Multi Stenosis on Hemodynamic Parameters in an Idealized Coronary Artery Model
Author(s): S. Kamangar
Keywords: Wall shear stress, Computational fluid dynamics, Non-Newtonian, Endothelial layer
The purpose of this study was to explore the influence of tandem (multi) stenosis on hemodynamic parameters in an idealized coronary artery models with varying severity of stenosis and interspace distance between the stenosis. A finite volume-based software package ANSYS CFX, was employed to model the blood flow. The blood was assumed as non-Newtonian, incompressible and pulsatile fluid. The hemodynamic parameters of blood, such as the wall shear stress (WSS), time average wall shear stress (TAWSS) and oscillatory shear index (OSI) was obtained and compared for various degree of stenosis and interspacing distance in various blood models. The computed results showed that as the interspacing distance between the stenosis decreases the low wall shear stress area increases for the model P70_D70 which could lead to further progression of stenosis in the distal region. There was no significant variation was observed for the model P70_D90, whereas the low WSS region increases as the distance between the proximal and distal stenosis increases for the model P90_D70. The highest TAWSS sites were created across the 90% AS (area stenosis) for all the cases. As the higher value of TAWSS is clinically significant since it could damage the endothelial layer. It is well known that the maximum value of OSI strongly associated with the critical areas of stenosis rupture. The maximum value of OSI was found at the proximal and distal stenosis for all the models simulated.

Journal of Applied Fluid Mechanics

The Journal of Applied Fluid Mechanics (JAFM) is an international, peer-reviewed journal which covers a wide range of theoretical, numerical and experimental aspects in fluid mechanics. The emphasis is on the applications in different engineering fields rather than on pure mathematical or physical aspects in fluid mechanics. Although many high quality journals pertaining to different aspects of fluid mechanics presently exist, research in the field is rapidly escalating.